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Gamla SiQiong hydrochloride orally disintegrating tablets are widely distributed in the body, the distribution volume is about 3.94 L/kg, gamla SiQiong hydrochloride orally disintegrating tablets of medicine, 48 hours after gamla SiQiong hydrochloride orally disintegrating tablets for about 12% of the dose in the form of a prototype drug excretion from urine and the rest in the form of metabolite excretion, urinary and fecal excretion rate were 48%, 38% respectively. Gamla SiQiong hydrochloride orally disintegrating tablets of the metabolism of liver microsomal enzymes P - 4503 - a mediated, gamla SiQiong hydrochloride orally disintegrating tablets and major metabolic pathways for N - demethylation fragrant after epoxidation with glucuronic acid. Gamla SiQiong hydrochloride orally disintegrating tablets of serum protein conjugation rate is about 65%.

Gamla SiQiong hydrochloride orally disintegrating tablets in healthy subjects single oral gamla SiQiong hydrochloride tablets on an empty stomach, after 1 mg gamla SiQiong hydrochloride orally disintegrating tablets of the peak plasma density is about 3.63 ng/ml, gamla SiQiong hydrochloride orally disintegrating tablets at the peak time of about 1.18 hours, gamla SiQiong hydrochloride orally disintegrating tablets of plasma elimination half-life of 6.23 hours, gamla SiQiong hydrochloride orally disintegrating tablets on cancer patients significantly prolong half-life, 9.8 11.6 hours. Gamla SiQiong hydrochloride orally disintegrating tablets high selectivity, without extrapyramidal reactions and side effects such as excessive sedation.

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